Case Study Category: Case studies

Discovery of ART0380, a Potent and Selective ATR Kinase Inhibitor Undergoing Phase 2 Clinical Studies for the Treatment of Advanced or Metastatic Solid Cancers

One of the hallmarks of cancer is high levels of DNA re […]

Case studies
2 8 月, 2026

Evaluation of anti-leukemic activity and underlying mechanisms of the novel GSPT1 degrader AB138 in acute myeloid leukemia

Acute myeloid leukemia (AML) is a relapsing and drug-re […]

Case studies
2 8 月, 2026

mRNAdesigner: an integrated web server for optimizingmRNA design and protein translation in eukaryotes

Messenger RNA (mRNA) therapy has revolutionized modern […]

Case studies
2 8 月, 2026

Exploration of a Class of Aryl Imidazolyl Ureas As Potent Acid Ceramidase Inhibitors for the Treatment of Fibrotic Diseases

Acid ceramidase (aCDase) is an essential enzyme in sphi […]

Case studies
2 8 月, 2026

A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition

Aberrant metabolism of cancer cells is well appreciated […]

Case studies
2 8 月, 2026

Boosting mRNA Therapeutics: pHLIP Enhances Endosomal Escape and Gene Expression in Lipid Nanoparticle

Messenger RNA (mRNA) has emerged as a transformative te […]

Case studies
2 8 月, 2026